NMR Theory and Techniques Course
2017, Wednesdays 4pm – 5pm in Chemistry G.54 with Ralph Adams unless specified.
1. Theory
| 1.1 | 18th January | Zochonis B | Nuclear magnetism and NMR spectroscopy | NMR Handout 1.1 | NMR Slides 1.1 | Lecture Capture Video |
| 1.2 | 25th January | Kilburn 1.1 | Chemical shift | NMR Handout 1.2 | NMR Slides 1.2 | Lecture Capture Video |
| 1.3 | 1st February | Chemistry G.54 | Spin-spin coupling | NMR Handout 1.3 | NMR Slides 1.3 | Lecture Capture Video |
| 1.4 | 8th February | Chemistry G.54 | The Fourier transform, 2D NMR, and non-uniform sampling with Mohammadali Foroozandeh |
NMR Handout 1.4 | NMR Slides 1.4 | Lecture Capture Video |
Recommended reading: P. J. Hore, Nuclear Magnetic Resonance
2. Techniques
| 2.1 | 15th February | Chemistry G.54 | Sensitivity, relaxation, quantification, signal averaging, and heteronuclei | NMR Handout 2.1 | NMR Slides 2.1 | Lecture Capture Video |
| 2.2 | 22nd February | Chemistry G.51 | Sensitivity enhancement, INEPT, DEPT, decoupling, and pure shift NMR with Laura Castañar |
NMR Handout 2.2 | NMR Slides 2.2 | Lecture Capture Video |
| 2.3 | 8th March | Chemistry G.51 | COSY and its variants, TOCSY, INADEQUATE and ADEQUATE with Laura Castañar |
NMR Handout 2.3 | NMR Slides 2.3 | Lecture Capture Video |
| 2.4 | 15th March | Chemistry G.54 | HSQC/HMQC, multiplicity edited HSQC, HMBC, H2BC, HSQCMBC, and HSQC-TOCSY with Peter Kiraly |
NMR Handout 2.4 | NMR Slides 2.4 | Lecture Capture Video |
| 2.5 | 22nd March | Chemistry G.54 | NOE, equilibrium and transient, 1D and 2D NOESY, selective NOESY, ROESY and HOESY | NMR Handout 2.5 | NMR Slides 2.5 | Lecture Capture Video |
| 2.6 | 29th March | Chemistry G.54 | J-resolved spectra, DOSY, and STD | NMR Handout 2.6 | NMR Slides 2.6 | Lecture Capture Video |
| 2.7 | 5th April | Chemistry G.54 | Chemical exchange, EXSY, kinetics, protein-ligand binding with Matthew Cliff |
Handout | Slides |
Recommended reading: T. D. W. Claridge, High-Resolution NMR Techniques in Organic Chemistry – available as an ebook through the library
3. Workshops (Dates to be confirmed)
| 3.1 | Processing 1D and 2D NMR data in MNova with Carlo Bawn |
Handout | Slides | Video Walkthrough | ||
| 3.2 | Processing 1D and 2D NMR data in Topspin with Carlo Bawn |
Handout | Slides | Video Walkthrough | ||
| 3.3 | Interpretation and assignment with Matthew Cliff |
Handout | Slides | Video Walkthrough |
